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This Web site is a component of the SAMHSA Health Information Network. |
Evidence-Based Practices: Shaping Mental Health Services Toward RecoveryIllness Management and Recovery WorkbookHandout 3:
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Both stress and biology contribute to
symptoms. |
What are the biological factors in mental illness?
The term “biological vulnerability” refers to people who are born with, or who acquire very early in life, a tendency to develop a problem in a specific medical area. For example, some people have a biological vulnerability to developing asthma, and other people have a biological vulnerability to developing high blood pressure or diabetes. Similarly, it is thought that people can have biological vulnerabilities to develop schizophrenia, bipolar disorder, or depression.
In diabetes, the part of the body that is affected is the pancreas, which keeps the level of insulin in balance. In mental illness, the part of the body that is affected is the brain, which is made up of billions of nerve cells (neurons) containing different chemicals (neurotransmitters). Scientists believe that mental illnesses are caused by imbalances in these neurotransmitters in the brain.
As with other disorders, such as diabetes, hypertension, and heart disease, genetic factors play a role in the vulnerability to mental illness. The chances of a person developing depression, bipolar disorder, or schizophrenia are higher if a close relative also has the disorder. Many scientific studies, including the international human genome project, are researching the genetic factors related to mental illness.
Genetic factors, however, do not explain everything about why some people develop mental illness. For example, for many people with mental illness, there is no history of anyone else in their family who experienced psychiatric symptoms. It is widely believed that non-genetic factors may also contribute to people developing mental illnesses. For example, early biological factors, such as exposure to a virus when the baby is in the womb, may be important.
There is little scientific evidence that alcohol use or drug use causes people to develop a biological vulnerability to mental illness in the first place. However, when someone already has a biological vulnerability, alcohol and drug use may trigger symptoms or make them worse.
Biology plays a part in whether
someone is vulnerable to developing a mental illness. |
Biological factors contribute to the chemical
imbalance in the brain that scientists have associated with psychiatric
symptoms. |
Questions:
Are you aware of any of your family members who have had (or might have had) a mental illness?
Have you had experience with alcohol or drugs that seemed to make your symptoms more severe?
What are the stress factors in mental illness?
Scientists believe that stress also plays an important part in psychiatric symptoms. Stress can trigger the onset of symptoms or make them worse. Stress may play a particularly strong role in increasing the biological vulnerability to depression. For example, if someone has lost a loved one, been the victim of a sexual or physical assault, witnessed a tragic event or experienced other examples of extraordinary stressors, he or she may be more likely to become depressed.
How people experience stress is very individual. In fact, what is stressful to one person may not be stressful at all to someone else. The following list, however, includes examples of situations that are commonly experienced as stressful:
There is no such thing as a stress-free life, so you can’t avoid all stress. In fact, to pursue important goals in your life, it is essential to be willing to take on new challenges, which can be stressful. But it is helpful to be aware of times when you’re under stress and to learn strategies for coping with it effectively. The educational handout “Coping with Stress and Common Problems” will go into more detail about this subject.
Stress can make symptoms worse or may
even trigger the onset of symptoms. |
Question: Have there been times when you were under stress and experienced
more symptoms?
What are the goals of treatment?
Because both biological vulnerability and stress contribute to symptoms, treatment for psychiatric symptoms needs to address both of these factors. The main goals of treatment are:
Reducing biological vulnerability
Medications help correct the chemical imbalances which lead to symptoms. There are different medicines to treat different types of symptoms. The educational handout “Using Medication Effectively” provides more specific information about medications and how to get the best results from them.
It is your decision whether to take medication. Medications are not perfect: they don’t cure mental illness and they have side effects. Medications also help some people more than others. However, medications are one of the most powerful tools we have for reducing or eliminating symptoms and preventing relapses and rehospitalizations.
Another way to reduce biological vulnerability is to avoid alcohol and drug abuse. Alcohol and drug use affect neurotransmitters in the brain, which can lead to worse symptoms and relapses. Alcohol and drug use can also lead to legal, financial, and health problems, resulting in stress that can trigger symptoms. In addition, using alcohol and drugs can interfere with the beneficial effects of medication.
| Medications and avoiding drug and alcohol
can reduce biological vulnerability. |
Questions:
Have medications helped you to reduce symptoms?
Has avoiding (or decreasing) drug and alcohol use helped you to reduce symptoms?
Reducing stress
Each person experiences stress in his or her own individual way. In addition, what is stressful to one person may not be stressful to another. For example, some people feel stressed by going to a large family gathering, whereas others enjoy it.
In general, the following guidelines are helpful in reducing common sources of stress:
Reducing stress can help reduce symptoms. |
Question: What do you do to reduce stress? You can use the following checklist
to answer the question.
Reducing Stress Checklist
| Strategy to reduce sources of stress | I use this strategy effectively |
I would like to use this strategy or improve the way I use this strategy |
| Be aware of situations that were stressful in the past | ||
| Set reasonable expectations for myself |
||
| Engage in meaningful activities | ||
| Maintain good health habits |
||
| Seek out supportive relationships | ||
| Avoid situations with arguments and criticism | ||
| Give myself credit for talents and strengths | ||
| Other: |
||
| Other: |
Coping with Stress
Stress is a natural part of life, and everyone experiences it. When stress occurs, however, it is helpful to have some strategies for dealing with it, so it will have a less harmful effect on you. Consider using some of the following strategies for dealing with stress:
Try to keep an open mind, and experiment with new ways of coping with stress. The more strategies you have, the better you can cope.
Developing strategies for dealing with
stress can help reduce symptoms. |
Question: What strategies do you use for coping with stress? You can use the
following checklist to answer the question.
Coping with Stress Checklist
| Strategy for coping with stress |
I use this strategy | I would like to try this strategy or improve the way I use it |
| Talk to someone about my feelings | ||
| Use relaxation techniques | ||
| Use positive self-talk | ||
| Keep a sense of humor | ||
| Use religion or other form of spirituality | ||
| Take a walk or exercise | ||
| Write in a journal | ||
| Express myself artistically | ||
| Work on solving problems | ||
| Engage in a hobby | ||
| Other: | ||
| Other: |
What kinds of treatment options are there to choose from?
There are many reasons for you to be as active as possible in your treatment:
Depending on your own individual situation and what is available in your community, you can choose among several different treatment options to best serve your needs. Some people choose one or two options; others choose several. A lot depends on your recovery goals.
The following chart lists some of the common recovery goals and the treatment
options that may help you move towards achieving your goals. This is only a
partial list. The educational handout, “Getting Your Needs Met in the
Mental Health System” will cover more options.
Treatment Options
| Recovery Goals | Treatment Options to Consider |
| Finding or maintaining a medication that is effective for me | • Psychiatrist • Medication group • Psychiatric nurse |
| Getting support and knowledge from other people who have experienced psychiatric
symptoms |
• Peer support groups • Psychosocial clubhouses • Group therapy • Additional self-help options as listed in the handout “Recovery Strategies” |
| Getting a job | • Supported employment • Vocational rehabilitation • Volunteer programs • Psychiatric rehabilitation |
| Solving some personal problems with the help of a professional or group | • Individual therapy • Group therapy |
| Improving communication skills |
• Social skills training groups • Group therapy |
| Improving family relationships |
• Family psychoeducation • Behavioral family therapy |
| Having structure and activity daily (provided by professionals) |
• Partial hospital program |
The more you learn about treatment, the
better choices you can make. |
Questions:
Which treatment options fit with your recovery goals?
Which of the options are you currently using?
Which would you like to try?
What are some examples of people whose treatment choices work well for them?
Even when people have the same disorder, they may experience symptoms very differently. Therefore, treatment choices vary widely depending on the individual and what works for them. The following are some examples of people whose treatment choices have worked well for them. Your choices may be very different—the important thing is that they work for you.
Example 1:
“I work part-time, and I’ve noticed that I need to take regular breaks or I start to feel stressed out. I always eat breakfast because if I skip it I start to feel irritable. Exercise helps me relax, so I try to jog every other day, before dinner. Just for 15-20 minutes, but it makes me feel good. I enjoy my life.”
“It took a long time to find a medication that worked well for me. But now I take it regularly and it helps me to concentrate better and not feel down all the time. I belong to a support group, which meets twice a month. It helps me to talk to people who have gone through some of the same things I have.
Example 2:
“When I first started to have symptoms and was toId the diagnosis, I learned everything I could about it. It helped me to make sense of what was happening, and it also made me feel like I wasn’t the only one. I also went to a recovery group that was led by someone who had mental illness. It gave me a lot of hope.
“I’ve gone to several different doctors, and I think the one I have now is good. She suggested trying one of the newer medicines because it has fewer side effects. I’m considering it. But I don’t want to change anything fast.
“I’ve been seeing a counselor every week to talk about some of the stress I’m under. He taught me how to do some yoga exercises to relax myself after the kids go to bed. I never thought I was the yoga type, but it does make me feel more relaxed.”
Example 3
“I go to group therapy every week. A couple of times each week I go to the clubhouse, where I can be with other people and have something fun to do. I’ve applied for a supported employment program, and I’m really excited about that.
“When I get stressed out, it helps me to sit down with my sketch pad and colored pencils and do some drawing. I put the best drawings up on my wall. I also like to go to the art museums and see paintings and drawings. It takes my mind to a calmer place.”
It’s important to choose treatment
options that work for you as an individual. |
Summary of the main points about the stress-vulnerability model and strategies for treatment
Appendix

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